Leica M-E Typ 220 has a 18.0MP Full frame (36 x 24 mm ) sized CCD sensor . You can shoot at maximum resolution of 5212 x 3472 pixels with aspect ratios of and 3:2. M-E Typ 220 has a native ISO range of 80 - 2500 and it can save files in RAW format which gives you a wider room for post processing.
Leica M-E Typ 220 is not the highest resolution Full frame camera. Blackmagic PYXIS 12K with its 98.8MP sensor is leading in this class. Check the comparison of Leica M-E Typ 220 vs Blackmagic PYXIS 12K or take a look at Highest resolution Mirrorless cameras list.
Leica M-E Typ 220 DxOMark Sensor Scores
DxOMark is a benchmark that scientifically assesses image quality of camera sensors. Leica M-E Typ 220 sensor has been tested by DxO Mark and got an overall score of 69 for its image quality. You can find the details of their analysis of Leica M-E Typ 220 here.
Let's look at how the size of the Leica M-E Typ 220's Full frame sensor compares with other standard sensor sizes.
Comparison image of Leica M-E Typ 220 Sensor Size with other standard sensors
Sensor size is what determines the circle of confusion, and therefore how much
depth of field Leica M-E Typ 220 gives you at any given aperture.
You can
calculate
the exact depth of field for the Leica M-E Typ 220
at any focal length, aperture and subject distance, including the hyperfocal distance
for landscapes and the very shallow focus zone you get with long telephoto lenses.