Leica M Typ 262 has a
24.0MP Full frame (35.8 x 23.9 mm ) sized CMOS sensor and features Maestro processor. On the other hand, Leica M-E Typ 220 has a
18.0MP Full frame (36 x 24 mm ) sized CCD sensor .
Leica M Typ 262's sensor provides 6MP more than Leica M-E Typ 220's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Below you can see the M Typ 262 and M-E Typ 220 sensor size comparison.
Sensor Size and Resolution Comparison image of Leica M Typ 262 and Leica M-E Typ 220 Cameras
Leica M Typ 262 and Leica M-E Typ 220 have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Leica M Typ 262
or the
Leica M-E Typ 220 ,
including hyperfocal distance.