Canon R5 II has a
45.0MP Full frame (36 x 24 mm ) sized Stacked CMOS sensor and features Digic X processor. On the other hand, Sony A7S II has a
12.0MP Full frame (35.6 x 23.8 mm ) sized CMOS sensor and features Bionz X processor.
Canon R5 II's sensor provides 33MP more than Sony A7S II's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Below you can see the R5 Mark II and A7S II sensor size comparison.
Sensor Size and Resolution Comparison image of Canon R5 II and Sony A7S II Cameras
Canon R5 II and Sony A7S II have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon R5 II
or the
Sony A7S II ,
including hyperfocal distance.