Canon 5DS R has a 51.0MP Full frame (36 x 24 mm ) sized CMOS sensor and features Dual DIGIC 6 processor. On the other hand, Sony A7R III has a 42.0MP Full frame (35.9 x 24 mm ) sized BSI-CMOS sensor and features Bionz X processor. Canon 5DS R's sensor provides 9MP more than Sony A7R III's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Another similarity between these two cameras is that both Sony A7R III and Canon 5DS R sensors lack anti-alias (Low-Pass) filters. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moire occurring in certain scenes.
Below you can see the 5DS R and A7R III sensor size comparison.
Canon 5DS R and Sony A7R III have almost the same sensor size so none of them has any significant advantage over other in providing control over depth of field when used with same focal length and aperture.