Fujifilm X-E3 has a 24.0MP APS-C (23.6 x 15.6 mm ) sized CMOS X-TRANS III sensor and features EXR Processor III processor. On the other hand, Nikon Z50 has a 21.0MP APS-C (23.5 x 15.7 mm ) sized BSI-CMOS sensor and features Expeed 6 processor.
Another similarity between these two cameras is that both Nikon Z50 and Fujifilm X-E3 sensors lack anti-alias (Low-Pass) filters. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moire occurring in certain scenes.
Below you can see the X-E3 and Z50 sensor size comparison.
Fujifilm X-E3 and Nikon Z50 have almost the same sensor size so none of them has any significant advantage over other in providing control over depth of field when used with same focal length and aperture.