Currently there are 2 native Telephoto Prime lenses for Nikon Z50 and 1 of these lenses are autofocus (AF) type.
Nikon Z50 doesn't have a sensor based image stabilization system and none of these lenses have optical Image Stabilization.
Since Nikon Z50 has environmental sealings (Weather Sealing), you may like to couple your camera with one of these 2 Telephoto Prime lenses with Weather Sealings.