Both Fujifilm X-E2S and Fujifilm X100S have APS-C sized 16.0 MP resolution sensors so sensor size and resolution is not a differentiator between these two cameras.
Another similarity between these two cameras is that both Fujifilm X100S and Fujifilm X-E2S sensors lack anti-alias (Low-Pass) filters. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the X-E2S and X100S sensor size comparison.
Sensor Size and Resolution Comparison image of Fujifilm X-E2S and Fujifilm X100S Cameras
Fujifilm X-E2S and Fujifilm X100S have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Fujifilm X-E2S
or the
Fujifilm X100S ,
including hyperfocal distance.