Canon R100 has a
24.0MP APS-C (22.3 x 14.9 mm ) sized CMOS sensor and features Digic 8 processor. On the other hand, Canon 4000D has a
18.0MP APS-C (22.3 x 14.9 mm ) sized CMOS sensor and features Digic 4+ processor.
Canon R100's sensor provides 6MP more than Canon 4000D's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Below you can see the R100 and 4000D sensor size comparison.
Sensor Size and Resolution Comparison image of Canon R100 and Canon 4000D Cameras
Canon R100 and Canon 4000D have the same sensor sizes so they will provide same level of control over the depth of field when used with same focal length and aperture. On the other hand, since Canon 4000D has 35% larger pixel area (18.54µm 2 vs 13.69µm 2 ) compared to Canon R100, it has larger pixel area to collect light hence potential to have less noise in low light / High ISO images.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon R100
or the
Canon 4000D ,
including hyperfocal distance.