Canon M100 has a
24.0MP APS-C (22.3 x 14.9 mm ) sized CMOS sensor and features DIGIC 7 processor. On the other hand, Nikon Z50 has a
21.0MP APS-C (23.5 x 15.7 mm ) sized BSI-CMOS sensor and features Expeed 6 processor.
One other difference between these two cameras that is worth mentioning is that Nikon Z50's sensor doesn't have an anti-alias (Low-Pass) filter. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the M100 and Z50 sensor size comparison.
Sensor Size and Resolution Comparison image of Canon M100 and Nikon Z50 Cameras
As seen above, Nikon Z50 has a 1.1x Larger sensor area than Canon M100. Larger sensors give photographer more control on the depth of field and blurry background compared to smaller sensor when shot in same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon M100
or the
Nikon Z50 ,
including hyperfocal distance.