The type of photography that you are planning to use is an important decision factor. Here we have evaluated the Canon 100-400mm f4.5-5.6L IS II USM and the Fujifilm XF 16-80mm F4 R OIS WR for their suitability to various photography scenarios:
Size and Weight Comparison
The size of a lens is a crucial factor to consider when comparing two lenses. Canon 100-400mm f4.5-5.6L IS II USM is the longer of the two lenses at 193mm. The Fujifilm XF 16-80mm F4 R OIS WR with a length of 89mm, is 104mm shorter. Besides being longer, the Canon 100-400mm f4.5-5.6L IS II USM also has a larger diameter of 94mm compared to the Fujifilm XF 16-80mm F4 R OIS WR's 78mm diameter.
The weight of a lens is equally significant as its external dimensions, particularly if you intend to handhold your camera and lens combination for extended periods. Fujifilm XF 16-80mm F4 R OIS WR weighs 440g, 72% (1150g) lighter than the Canon 100-400mm f4.5-5.6L IS II USM's weight of 1590g.
Filter Threads
The Canon 100-400mm f4.5-5.6L IS II USM has a filter size of 77mm whereas the Fujifilm XF 16-80mm F4 R OIS WR has a 72mm diameter. Larger filters are generally more expensive than the smaller ones given all the other features are equal.
Below are links to the 77mm filters that we recommend you to consider for the Canon 100-400mm f4.5-5.6L IS II USM:
And these are the 72mm filters that we recommend for the Fujifilm XF 16-80mm F4 R OIS WR:
Lens Mounts
The Canon 100-400mm f4.5-5.6L IS II USM has the Canon EF lens mount whereas the Fujifilm XF 16-80mm F4 R OIS WR has the Fujifilm X lens mount. Some of the latest released cameras that are compatible with these mounts are Blackmagic URSA 12K LF, Z CAM E2-F6 II 6K and Z CAM E2-S6 II 6K for the Canon EF Mount and Fujifilm X-T30 III, Fujifilm X-E5 and Fujifilm X-M5 for the Fujifilm X Mount.
Focal Range
Canon 100-400mm f4.5-5.6L IS II USM has a focal range of 100-400mm and
4.0X zoom ratio . When it is mounted on an APS-C sensor camera with 1.6x crop, it provides a 35mm (FF) equivalent of
160 - 640mm.
On the other hand, the Fujifilm XF 16-80mm F4 R OIS WR has a focal range of 16-80mm and 5.0X zoom ratio which has an effective (full-frame 35mm equivalent) focal range of 24-120mm when used on a APS-C / DX format camera.