Panasonic S1R II has a
44.3MP Full frame (36 x 24 mm ) sized CMOS sensor and features Venus Engine processor. On the other hand, Canon R5 has a
45.0MP Full frame (36 x 24 mm ) sized CMOS sensor and features Digic X processor.
Another difference between these two cameras is that Panasonic S1R II's sensor lacks anti-alias (Low-Pass) filter. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the S1R II and R5 sensor size comparison.
Sensor Size and Resolution Comparison image of Panasonic S1R II and Canon R5 Cameras
Panasonic S1R II and Canon R5 have the same sensor sizes so they will provide same level of control over the depth of field when used with same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Panasonic S1R II
or the
Canon R5 ,
including hyperfocal distance.