Both Nikon D7500 and Nikon Z50 have APS-C sized 21.0 MP resolution sensors so sensor size and resolution is not a differentiator between these two cameras.
Another similarity between these two cameras is that both Nikon Z50 and Nikon D7500 sensors lack anti-alias (Low-Pass) filters. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the D7500 and Z50 sensor size comparison.
Sensor Size and Resolution Comparison image of Nikon D7500 and Nikon Z50 Cameras
Nikon D7500 and Nikon Z50 have the same sensor sizes so they will provide same level of control over the depth of field when used with same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Nikon D7500
or the
Nikon Z50 ,
including hyperfocal distance.