Both Canon S100 and Canon G16 have 1/1.7-inch sized 12.0 MP resolution sensors so sensor size and resolution is not a differentiator between these two cameras.
Below you can see the S100 and G16 sensor size comparison.
Sensor Size and Resolution Comparison image of Canon S100 and Canon G16 Cameras
Canon S100 and Canon G16 have the same sensor sizes so they will provide same level of control over the depth of field when used with same focal length and aperture.
DxOMark Sensor Scores
DxOMark is a benchmark that scientifically assesses image quality of camera sensors. It scores camera sensors for color depth (DXO Portrait), dynamic range (DXO Landscape) and low-light sensitivity (DXO Sports), and also gives them an overall score. Canon S100 and Canon G16 sensors have been tested by DxO and the results show that G16 has a better overall score of 54, 4 points higher compared to S100's score of 50.
Model
Overall
Color Depth
Dynamic Range
Low-light ISO
Canon S100
50
20.7 bits
11.6 Evs
153 ISO
Canon G16
54
21.0 bits
11.7 Evs
230 ISO
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon S100
or the
Canon G16 ,
including hyperfocal distance.