Canon R6 III has a
32.5MP Full frame (36 x 24 mm ) sized CMOS sensor and features Digic X processor. On the other hand, Panasonic S1 IIE has a
24.0MP Full frame (35.6 x 23.8 mm ) sized CMOS sensor and features Venus Engine processor.
Canon R6 III's sensor provides 8.5MP more than Panasonic S1 IIE's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
One other difference between these two cameras that is worth mentioning is that Panasonic S1 IIE's sensor doesn't have an anti-alias (Low-Pass) filter. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the R6 III and S1 IIE sensor size comparison.
Sensor Size and Resolution Comparison image of Canon R6 III and Panasonic S1 IIE Cameras
Canon R6 III and Panasonic S1 IIE have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon R6 III
or the
Panasonic S1 IIE ,
including hyperfocal distance.