Canon M50 II has a
24.0MP APS-C (22.3 x 14.9 mm ) sized CMOS sensor and features Digic 8 processor. On the other hand, Fujifilm S5 Pro has a
6.0MP APS-C (23 x 15.5 mm ) sized CCD sensor .
Canon M50 II's sensor provides 18MP more than Fujifilm S5 Pro's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Below you can see the M50 Mark II and S5 Pro sensor size comparison.
Canon M50 II and Fujifilm S5 Pro have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.