Canon 6D MII has a
26.0MP Full frame (35.9 x 24 mm ) sized CMOS sensor and features DIGIC 7 processor. On the other hand, Panasonic S5 II has a
24.0MP Full frame (35.6 x 23.8 mm ) sized CMOS sensor and features Venus Engine processor.
One other difference between these two cameras that is worth mentioning is that Panasonic S5 II's sensor doesn't have an anti-alias (Low-Pass) filter. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the 6D MII and S5 Mark II sensor size comparison.
Sensor Size and Resolution Comparison image of Canon 6D MII and Panasonic S5 II Cameras
Canon 6D MII and Panasonic S5 II have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon 6D MII
or the
Panasonic S5 II ,
including hyperfocal distance.
