Both Canon 5DS R and Canon 5DS have Full frame sized 51.0 MP resolution sensors so sensor size and resolution is not a differentiator between these two cameras.
Another difference between these two cameras is that Canon 5DS R's sensor lacks anti-alias (Low-Pass) filter. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the 5DS R and 5DS sensor size comparison.
Sensor Size and Resolution Comparison image of Canon 5DS R and Canon 5DS Cameras
Canon 5DS R and Canon 5DS have the same sensor sizes so they will provide same level of control over the depth of field when used with same focal length and aperture.
DxOMark Sensor Scores
DxOMark is a benchmark that scientifically assesses image quality of camera sensors. It scores camera sensors for color depth (DXO Portrait), dynamic range (DXO Landscape) and low-light sensitivity (DXO Sports), and also gives them an overall score. Canon 5DS R and Canon 5DS sensors have been tested by DxO and the results show that 5DS has a better overall score of 87, 1 points higher compared to 5DS R's score of 86.
Model
Overall
Color Depth
Dynamic Range
Low-light ISO
Canon 5DS R
86
24.6 bits
12.4 Evs
2308 ISO
Canon 5DS
87
24.7 bits
12.4 Evs
2381 ISO
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon 5DS R
or the
Canon 5DS ,
including hyperfocal distance.