Both Canon 300D and Nikon D50 have APS-C sized 6.0 MP resolution sensors so sensor size and resolution is not a differentiator between these two cameras.
Below you can see the 300D and D50 sensor size comparison.
Sensor Size and Resolution Comparison image of Canon 300D and Nikon D50 Cameras
Canon 300D and Nikon D50 have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
DxOMark Sensor Scores
At Camera Decision, we also look at Dxo Mark sensors when available as we think it is a good indicator of image quality.
Model
Overall
Color Depth
Dynamic Range
Low-light ISO
Canon 300D
55
21.0 bits
10.8 Evs
544 ISO
Nikon D50
55
20.9 bits
10.8 Evs
560 ISO
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Canon 300D
or the
Nikon D50 ,
including hyperfocal distance.