The type of photography that you are planning to use is an important decision factor. Here we have evaluated the Sigma 90mm F2.8 DG DN C and the Sigma 65mm F2 DG DN for their suitability to various photography scenarios:
Size and Weight Comparison
The size of a lens is a crucial factor to consider when comparing two lenses. Sigma 65mm F2 DG DN is the longer of the two lenses at 75mm. The Sigma 90mm F2.8 DG DN C with a length of 60mm, is 15mm shorter. Besides being longer, the Sigma 65mm F2 DG DN also has a larger diameter of 72mm compared to the Sigma 90mm F2.8 DG DN C's 64mm diameter.

Sigma 65mm F2 DG DN vs Sigma 90mm F2.8 DG DN C Lenses Size Comparison
The weight of a lens is equally significant as its external dimensions, particularly if you intend to handhold your camera and lens combination for extended periods. Sigma 90mm F2.8 DG DN C weighs 295g, which means it is 110g (27%) lighter than the Sigma 65mm F2 DG DN which has a weight of 405g.
Filter Threads
The Sigma 90mm F2.8 DG DN C has a filter size of 55mm whereas the Sigma 65mm F2 DG DN has a 62mm diameter. Larger filters are generally more expensive than the smaller ones given all the other features are equal.
Below are links to the 55mm filters that we recommend you to consider for the Sigma 90mm F2.8 DG DN C:
And these are the 62mm filters that we recommend for the Sigma 65mm F2 DG DN:
Lens Mounts
The Sigma 90mm F2.8 DG DN C has the Sony E lens mount whereas the Sigma 65mm F2 DG DN has the Leica L lens mount. Some of the latest released cameras that are compatible with these mounts are Sony FX5, Sony A7R VI and Sony A7 V for the Sony E Mount and Leica SL3-P, Panasonic S1 II and Panasonic S1 IIE for the Leica L Mount.
Sigma 90mm F2.8 DG DN C is also available in the Leica L mount.
Sigma 65mm F2 DG DN is also available in Sony E mount.
Focal Range
Sigma 90mm F2.8 DG DN C is a prime lens with fixed focal lenght of 90mm.
On the other hand, the Sigma 65mm F2 DG DN is a prime lens with fixed focal lenght of 65mm.