Environmental Sealings For a camera that you carry everywhere with you, being weather proofed is a big advantage. You will have one less thing to worry about.
Large Medium format (44 x 33 mm) sensor Large sensor in Fujifilm GFX 50S ensures a good low light image quality compared to smaller sensor, and it also provide shallow depth of field and a nice blurry background when needed.
Medium size Body With relatively smaller body compared to DSLRs and better ergonomics compared to Compacts,Fujifilm GFX 50Sis a good compromise between size and functionality.
740g Carrying this weight all day may not be very comfortable for you.
Body Thickness 91mm With a thickness of 91mm,Fujifilm GFX 50S is not a pocketable camera for sure.