Panasonic S1R has a 47.0MP Full frame (36 x 24 mm ) sized CMOS sensor and features Venus Engine processor. On the other hand, Leica SL has a 24.0MP Full frame (36 x 24 mm ) sized CMOS sensor and features Maestro II processor.
Panasonic S1R's sensor provides 23MP more than Leica SL's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Another similarity between these two cameras is that both Leica SL and Panasonic S1R sensors lack anti-alias (Low-Pass) filters. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moire occurring in certain scenes.
Below you can see the S1R and SL sensor size comparison.
Panasonic S1R and Leica SL have sensor sizes so they will provide same level of control over the depth of field when used with same focal length and aperture. On the other hand, since Leica SL has 100% larger pixel area (36.00µm2 vs 18.00µm2) compared to Panasonic S1R, it has larger pixel area to collect light hence potential to have less noise in low light / High ISO images.
DxOMark Sensor Scores
Both Panasonic S1R and Leica SL sensors have been tested by DxoMark. DxoMark scores camera sensors for color depth (DXO Portrait), dynamic range (DXO Landscape) and low-light sensitivity (DXO Sports), and also gives them an overall score. Of the two cameras that we are comparing, S1R has scored 100, 12 points higher than SL.