Both Nikon Z6 III and Panasonic S1 have Full frame sized 24.0 MP resolution sensors so sensor size and resolution is not a differentiator between these two cameras.
One other difference between these two cameras that is worth mentioning is that Panasonic S1's sensor doesn't have an anti-alias (Low-Pass) filter. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moiré occurring in certain scenes.
Below you can see the Z6 Mark III and S1 sensor size comparison.
Sensor Size and Resolution Comparison image of Nikon Z6 III and Panasonic S1 Cameras
Nikon Z6 III and Panasonic S1 have almost the same sensor size, so neither of them has any significant advantage over the other in terms of providing control over depth of field when used with the same focal length and aperture.
Sensor size sets the circle of confusion, so it drives how much depth of field each
of these bodies gives you at a given aperture. You can calculate it exactly for the
Nikon Z6 III
or the
Panasonic S1 ,
including hyperfocal distance.
