Leica SL2 has a 47.0MP Full frame (36 x 24 mm ) sized CMOS sensor and features Maestro III processor. On the other hand, Panasonic GH5S has a 10.0MP Four Thirds (17.3 x 13 mm ) sized CMOS sensor and features Venus Engine 10 processor.
Leica SL2's sensor provides 37MP more than Panasonic GH5S's sensor, which gives a significant advantage in real life. You can print your images larger or crop more freely.
On the other hand, please keep in mind that Max sensor resolution is not the only determinant of resolving power. Factors such as the optical elements, low pass filter, pixel size and sensor technology also affects the final resolution of the captured image.
Another similarity between these two cameras is that both Panasonic GH5S and Leica SL2 sensors lack anti-alias (Low-Pass) filters. Removing anti-alias filter increases the sharpness and level of detail but at the same time, it increases the chance of moire occurring in certain scenes.
Below you can see the SL2 and GH5S sensor size comparison.
As seen above, Leica SL2 has a 3.8x Larger sensor area than Panasonic GH5S. Larger sensors give photographer more control on the depth of field and blurry background compared to smaller sensor when shot in same focal length and aperture.