For a camera that you carry everywhere with you, being weather proofed is a big advantage. You will have one less thing to worry about. Large APS-C (23.5 x 15.7 mm) sensor
Large sensor in Nikon D500 ensures a good low light image quality compared to smaller sensor, and it also provide shallow depth of field and a nice blurry background when needed.
Even the smallest lens attached to this body will be a burden to carry everywhere with you. 860g
Carrying this weight all day may not be very comfortable for you. Body Thickness 81mm
With a thickness of 81mm,Nikon D500 is not a pocketable camera for sure.