Size and weight is a big decision factor when you are trying to find the ideal camera for your needs.
In this section, We are going to illustrate Nikon D80 and Canon ELPH 330 HS side-by-side from the front, back and top in their relative dimensions. Nikon D80 has external dimensions of 132 x 103 x 77 mm (5.2 x 4.06 x 3.03″) and weighs 668 g (1.47 lb / 23.56 oz) (including batteries). Canon ELPH 330 HS has external dimensions of 97 x 56 x 23 mm (3.82 x 2.2 x 0.91″) and weighs 144 g (0.32 lb / 5.08 oz) (including batteries).
Below you can see the front view size comparison of Nikon D80 and Canon ELPH 330 HS. Canon ELPH 330 HS is clearly the smaller of the two cameras. Its body is 35mm narrower, 47mm shorter and 54mm thinner than Nikon D80. As you can tell, actually this is not a fair size comparison since Canon ELPH 330 HS has a built-in lens but Nikon D80 doesn't. Once you put a lens on D80, its thickness will increase significantly.
Comparison image of Nikon D80 and Canon ELPH 330 HS Size, Weight and External Dimensions - Front View
Now lets look at the top view comparison of Nikon D80 and Canon ELPH 330 HS.
Top View Comparison image of Nikon D80 and Canon ELPH 330 HS Size
Weight is another important factor especially when deciding on a camera that you want to carry with you all day.
Canon ELPH 330 HS is significantly lighter (524g ) than the Nikon D80 which may become a big advantage especially on long walking trips.
Again, this comparison may not be very useful in real life as we are comparing the weight of a camera with a built-in lens to the body-only weight of an interchangeable lens camera. Once you put a lens on D80, the total kit will weigh much higher.
Weather Sealing
Unfortunately neither Nikon D80 nor Canon PowerShot ELPH 330 HS (IXUS 255 HS) provides any type of weather sealing in their body, so you have to give extra care especially when you are shooting outdoors. If weather sealing is a must-have feature for you, check these sections: Top DSLR Cameras with Weather Sealing Top Compact Cameras with Weather Sealing
LCD Screen Size and Features
Canon ELPH 330 HS's 3" LCD screen is slightly larger than Nikon D80's 2.5" screen.
Unfortunately, both cameras has fixed screens so they don't tilt or flip in directions.