Size and weight is a big decision factor when you are trying to find the ideal camera for your needs.
In this section, We are going to illustrate Nikon S6100 and Leica M-E Typ 220 side-by-side from the front, back and top in their relative dimensions. Nikon S6100 has external dimensions of 98 x 58 x 27 mm (3.86 x 2.28 x 1.06″) and weighs 175 g (0.39 lb / 6.17 oz) (including batteries). Leica M-E Typ 220 has external dimensions of 139 x 80 x 37 mm (5.47 x 3.15 x 1.46″) and weighs 585 g (1.29 lb / 20.64 oz) (including batteries).
Below you can see the front view size comparison of Nikon S6100 and Leica M-E Typ 220. Nikon S6100 is clearly the smaller of the two cameras. Its body is 41mm narrower, 22mm shorter and 10mm thinner than Leica M-E Typ 220. As you can tell, actually this is not a fair size comparison since Nikon S6100 has a built-in lens but Leica M-E Typ 220 doesn't. Once you put a lens on M-E Typ 220, its thickness will increase significantly.
Comparison image of Nikon S6100 and Leica M-E Typ 220 Size, Weight and External Dimensions - Front View
Here is the back view size comparison of Nikon S6100 and Leica M-E Typ 220.
Comparison image of Nikon S6100 and Leica M-E Typ 220 Size and Weight - Back View
Now lets look at the top view comparison of Nikon S6100 and Leica M-E Typ 220.
Top View Comparison image of Nikon S6100 and Leica M-E Typ 220 Size
Weight is another important factor especially when deciding on a camera that you want to carry with you all day.
Nikon S6100 is significantly lighter (410g ) than the Leica M-E Typ 220 which may become a big advantage especially on long walking trips.
Again, this comparison may not be very useful in real life as we are comparing the weight of a camera with a built-in lens to the body-only weight of an interchangeable lens camera. Once you put a lens on M-E Typ 220, the total kit will weigh much higher.
Weather Sealing
Unfortunately neither Nikon Coolpix S6100 nor Leica M-E Typ 220 provides any type of weather sealing in their body, so you have to give extra care especially when you are shooting outdoors. If weather sealing is a must-have feature for you, check these sections: Top Compact Cameras with Weather Sealing Top Mirrorless Cameras with Weather Sealing
LCD Screen Size and Features
Nikon S6100's 3" LCD screen is slightly larger than Leica M-E Typ 220's 2.5" screen.
Unfortunately, both cameras has fixed screens so they don't tilt or flip in directions.