Both Nikon P500 and Casio EX-100 have 12.0 MP resolution sensors but Nikon P500's sensor is 1/2.3-inch (6.17 x 4.55 mm ) and Casio EX-100's sensor is 1/1.7-inch (7.44 x 5.58 mm ).
Since Casio EX-100's has a larger sensor area with the same resolution, this means that it also has a larger pixel area hence better light collecting capacity for a given aperture compared to Nikon P500.
Below you can see the P500 and EX-100 sensor size comparison.
Sensor Size and Resolution Comparison image of Nikon P500 and Casio EX-100 Cameras
As seen above, Casio EX-100 has a 1.5x Larger sensor area than Nikon P500. Larger sensors give photographer more control on the depth of field and blurry background compared to smaller sensor when shot in same focal length and aperture.