Here we are comparing two cameras with different body types: Fujifilm GFX 50S, which was introduced in January 2017 is a Pro Mirrorless camera with a 51.0MP Medium format sensor whereas Nikon D500, which was introduced in January 2016 is a Semi-Pro DSLR camera with a 21.0MP APS-C sensor.
Despite some fundamental differences of these two body types, Mirrorless cameras are becoming serious alternatives to DSLR cameras thanks to their size/weight advantages and recent improvements in their focus speeds , which makes this comparison even more interesting. Fortunately, you can't go wrong with any of these cameras as we rank them amongst Top 10 cameras in their classes. Fujifilm GFX 50S is ranked #2
out of 39 Pro Mirrorless cameras with an overall score of 99 whereas Nikon D500 is ranked #7
out of 90 Semi-Pro DSLR cameras with an overall score of 86.
Let's have a brief look at the main features of Fujifilm GFX 50S and Nikon D500 before getting into our more detailed comparison.